Gerard Apodaca, PhD

Conceptual Schematic

THE THREE MOST SIGNIFICANT QUESTIONS THAT DEFINE YOUR RESEARCH PROGRAM:
How is membrane traffic regulated by mechanical forces?
How do defects in Uroplakin3 signaling lead to congenital anomalies of the kidney and urinary tract?
How do umbrella cell tight junctions accommodate changes in bladder filling and voiding?

FIVE KEYWORDS THAT DESCRIBE YOUR AREAS OF INTEREST:
Epithelial biology, urothelium, endocytosis, exocytosis, mechanotransduction

TECHNIQUES, MODELS, METHODS, ANALYTIC APPROACHES, ETC:
Light and electron microscopy
Biochemistry
Epithelial tissue physiology
Analysis of membrane traffic
Protein/shRNA expression in tissues