Partha Dutta, PhD, DVM

Conceptual Schematic

THE THREE MOST SIGNIFICANT QUESTIONS THAT DEFINE YOUR RESEARCH PROGRAM:
Do macrophages of different origins react differently in inflammation?
What are the molecular signals that regulate myeloid cell production from hematopoietic stem cells after myocardial infarction?
What are the local vs. systemic signals that activate hematopoietic stem cells in pulmonary hypertension?

FIVE KEYWORDS THAT DESCRIBE YOUR AREAS OF INTEREST:
1. Macrophages
2. Hematopoietic Stem Cells
3. Inflammation
4. Myocardial Infarction
5. Tissue remodeling

TECHNIQUES, MODELS, METHODS, ANALYTIC APPROACHES, ETC:
Multi color low cytometry (up to 15 colors)
Intravital microscopy of myeloid cells
Mouse strains for genetic fate mapping
Systems biology approach to disease
Mouse models of cardiovascular disease