Charles F. McTiernan, PhD

Conceptual Schematic

THE THREE MOST SIGNIFICANT QUESTIONS THAT DEFINE YOUR RESEARCH PROGRAM:
Is human peripartum cardiomyopathy (PPCM) mediated by immune processes?
Does a murine model recapitulate human PPCM?
Do circadian patterns of cardiac gene expression explain circadian patterns of cardiac arrhythmias?

FIVE KEYWORDS THAT DESCRIBE YOUR AREAS OF INTEREST:
Heart failure mechanisms,
Cardiac fibrosis,
Cardiac function,
Pregnancy-associated immune processes,
Circadian gene expression

TECHNIQUES, MODELS, METHODS, ANALYTIC APPROACHES, ETC:
Murine transgenic models; heart failure Murine cardiac function; echocardiography Gene and protein expression; RTPCR, western, immunofluorescent microscopy Human cardiac tissues