Guy Salama, PhD

Conceptual Schematic

THE THREE MOST SIGNIFICANT QUESTIONS THAT DEFINE YOUR RESEARCH PROGRAM:
Development of new technology for cardiac electrophysiology
Mechanisms underlying arrhythmia risks as a function of sex, heart failure and atrial fibrillation
Excitation-contraction coupling

FIVE KEYWORDS THAT DESCRIBE YOUR AREAS OF INTEREST:
Voltage sensitive dyes, Relaxin, Sex steroids, Fibrosis, Extracellular K+-accumulation

TECHNIQUES, MODELS, METHODS, ANALYTIC APPROACHES, ETC:
Dual optical mapping of voltage and Calcium
Ca2+ fluxes across sarcoplasmic reticulum
Whole-cell voltage-clamp technique
Fluorescence sensors for K+ and Na+ ions
Isolation of adult myocytes and human myocytes derived from induced pluripotent stem cells