Ora A. Weisz, PhD

Conceptual Schematic

THE THREE MOST SIGNIFICANT QUESTIONS THAT DEFINE YOUR RESEARCH PROGRAM:
How do proximal tubule cells of the kidney establish and maintain an extraordinarily robust apical endocytic capacity?

How do proximal tubule cells sense and respond to the changes in fluid shear stress that accompany alterations in glomerular filtration rate?

What are the mechanistic bases of genetic diseases and other conditions that result in tubular proteinuria?

FIVE KEYWORDS THAT DESCRIBE YOUR AREAS OF INTEREST:
Membrane traffic, Mechanosensation, Cell polarity, Cilia, Cytoskeleton

TECHNIQUES, MODELS, METHODS, ANALYTIC APPROACHES, ETC:
Confocal microscopy, Protein trafficking, Glycosylation, Kidney slice cultures